DNA methylation in tomato fruit ripening

• Published in: Physiologia plantarum Vol. 174; no. 1; pp. e13627 - n/a
• Main Authors: Liu, Zhiya, Wu, Xuetong, Liu, Huwei, Zhang, Meiling, Liao, Weibiao
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.2022; Wiley Subscription Services, Inc
• Subjects: Cytosine; Demethylation; Deoxyribonucleic acid; DNA; DNA demethylase; DNA methylation; DNA Methylation - genetics; Epigenetics; Ethylenes; Flowering; Fruit - physiology; Fruits; Gene Expression Regulation, Plant; Lycopersicon esculentum; Methyltransferase; Nutritive value; Plant Proteins - metabolism; Plants (botany); Ripening; Tomatoes; Transcription factors
• ISSN: 0031-9317; 1399-3054
• DOI: 10.1111/ppl.13627

Fleshy fruit, the most economical and nutritional value unique to flowering plants, is an important part of our daily diet. Previous studies have shown that fruit ripening is regulated by transcription factors and the plant hormone ethylene, but recent research has also shown that epigenetics also plays an essential role, especially DNA methylation. DNA methylation is the process of transferring –CH3 to the fifth carbon of cytosine residues under the action of methyltransferase to form 5‐methylcytosine (5‐mC). So far, most works have been focused on tomato. Tomato ripening is dynamically regulated by DNA methylation and demethylation, but the understanding of this mechanism is still in its infancy. The dysfunction of a DNA demethylase, DEMETER‐like DNA demethylases 2 (DML2), prevents the ripening of tomato fruits, but immature fruits ripen prematurely under the action of DNA methylation inhibitors. Additionally, studies have shown that the relationship between fruit quality and DNA methylation is not linear, but the specific molecular mechanism is still unclear. Here, we review the recent advances in the role of DNA methylation in tomato fruit ripening, the interaction of ripening transcription factors and DNA methylation, and its effects on quality. Then, a number of questions for future research of DNA methylation regulation in tomato fruit ripening is proposed.