Trimethylamine N‐oxide as a risk marker for ischemic stroke in patients with atrial fibrillation

• Published in: Journal of biochemical and molecular toxicology Vol. 33; no. 2; pp. e22246 - n/a
• Main Authors: Liang, Zhaoguang, Dong, Zengxiang, Guo, Meihua, Shen, Zhaoqian, Yin, Dechun, Hu, Shuang, Hai, Xin
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.02.2019
• Subjects: Aged; atrial fibrillation (AF); Atrial Fibrillation - blood; Atrial Fibrillation - complications; Biomarkers - blood; Brain Ischemia - blood; Brain Ischemia - etiology; Cardiac arrhythmia; Cardiovascular diseases; Confidence intervals; Female; Fibrillation; Health risks; Humans; Ischemia; ischemic stroke (IS); Male; Methylamines - blood; Middle Aged; Patients; Plasma levels; Regression analysis; Risk analysis; Risk Factors; Statistical analysis; Stroke; Stroke - blood; Stroke - etiology; Trimethylamine; trimethylamine N‐oxide (TMAO); atrial fibrillation (AF); trimethylamine N-oxide (TMAO); ischemic stroke (IS); risk factors

Trimethylamine N‐oxide (TMAO) is an independent risk factor of cardiovascular disease. Our objective was to explore the relation between TMAO and ischemic stroke (IS) in patients with atrial fibrillation (AF). A total of 68 patients with AF with IS and 111 ones without IS were enrolled. The plasma l...