The nature and consequences of co‐infections in tilapia: A review

• Published in: Journal of fish diseases Vol. 43; no. 6; pp. 651 - 664
• Main Authors: Abdel‐Latif, Hany M. R., Dawood, Mahmoud A. O., Menanteau‐Ledouble, Simon, El‐Matbouli, Mansour
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.06.2020
• Subjects: Concurrent infection; co‐infections; Disease; Diseases; Fish; Freshwater fishes; Health services; Infections; Outbreaks; Pathogenicity; Pathogens; Species; susceptibility; synergistic interactions; Tilapia; tilapia; susceptibility; co-infections; synergistic interactions
• ISSN: 0140-7775; 1365-2761
• DOI: 10.1111/jfd.13164

Co‐infections commonly arise when two or multiple different pathogens infect the same host, either as simultaneous or as secondary concurrent infection. This potentiates their pathogenic effects and leads to serious negative consequences on the exposed host. Numerous studies on the occurrence of the bacterial, parasitic, fungal and viral co‐infections were conducted in various tilapia species. Co‐infections have been associated with serious negative impacts on susceptible fish because they increase the fish susceptibility to diseases and the likelihood of outbreaks in the affected fish. Co‐infections can alter the disease course and increase the severity of disease through synergistic and, more rarely, antagonistic interactions. In this review, reports on the synergistic co‐infections and their impacts on the affected tilapia species are highlighted. Additionally, their pathogenic mechanisms are briefly discussed. Tilapia producers should be aware of the possible occurrence of co‐infections and their effects on the affected tilapia species and in particular of the clinical signs and course of the disease. To date, there is still limited information regarding the pathogenicity mechanisms and pathogen interactions during these co‐infections. This is generally due to low awareness regarding co‐infections, and in many cases, a dominant pathogen is perceived to be of vital importance and hence becomes the target of treatment while the treatment of the co‐infectious agents is neglected. This review article aimed at raising awareness regarding co‐infections and helping researchers and fish health specialists pay greater attention to these natural cases, leading to increased research and more consistent diagnosis of co‐infectious outbreaks in order to improve control strategies to protect tilapia when infected with multiple pathogens.