Breast cancer survival following MRI detection in a high‐risk screening program

Guidelines for high‐risk screening with MRI were introduced by the American Cancer Society in 2007, based on superior sensitivity of MRI over mammography, albeit without proven mortality reduction. The mortality end point is still unconfirmed, but international data are maturing with improved surviv...

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Bibliographic Details
Published inThe breast journal Vol. 26; no. 5; pp. 991 - 994
Main Authors Hollingsworth, Alan B., Pearce, Melanie R., Stough, Rebecca G.
Format Journal Article
LanguageEnglish
Published United States John Wiley & Sons, Inc 01.05.2020
Subjects
Breast cancer
breast cancer survival
breast MRI
high‐risk screening
Invasiveness
Lead time
Magnetic resonance imaging
Mammography
Mortality
MRI‐detected breast cancer
Survival
breast MRI
MRI-detected breast cancer
high-risk screening
breast cancer survival
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ISSN1075-122X
1524-4741
1524-4741
DOI10.1111/tbj.13813

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Summary:Guidelines for high‐risk screening with MRI were introduced by the American Cancer Society in 2007, based on superior sensitivity of MRI over mammography, albeit without proven mortality reduction. The mortality end point is still unconfirmed, but international data are maturing with improved survival apparent, albeit subject to lead time and length bias. In this observational study of survival, we review 41 consecutive patients whose cancers (85.3% invasive) were detected through 2039 asymptomatic MRI screenings. With a minimum follow‐up of 5 years and median follow‐up of 10.2 years (range: 5.0‐15.1), disease‐specific survival is 100%.
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ISSN:1075-122X
1524-4741
1524-4741
DOI:10.1111/tbj.13813