Blistering severe cutaneous adverse reactions in children: proposal for paediatric‐focused clinical criteria

Severe cutaneous adverse reactions (SCARs) are challenging to diagnose and manage in children for two main reasons: 1) The literature on SCARs in children is sparse and extrapolated from adult data, 2) Many paediatric blistering SCAR cases are qualified as 'atypical' or 'incomplete�...

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Published inBritish journal of dermatology (1951) Vol. 185; no. 2; pp. 447 - 449
Main Authors Ramien, M.L., Bahubeshi, A., Lara‐Corrales, I., Pope, E., Levy, M.L., Nopper, A.J., Shear, N.H., Eichenfield, L.
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.08.2021
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Summary:Severe cutaneous adverse reactions (SCARs) are challenging to diagnose and manage in children for two main reasons: 1) The literature on SCARs in children is sparse and extrapolated from adult data, 2) Many paediatric blistering SCAR cases are qualified as 'atypical' or 'incomplete' erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) because certain clinical features make them not fit into this adult classification. Our panel proposes paediatric-focused clinical criteria for blistering SCARs in children to improve early diagnosis and facilitate acute management.
ISSN:0007-0963
1365-2133
DOI:10.1111/bjd.20063