Disseminated lymphangiomas as a cutaneous manifestation of Noonan syndrome

Lymphangioma is a known, but rare manifestation of Noonan syndrome. We present the case of disseminated and circumscribed cutaneous lymphangiomas in the context of Noonan syndrome. Oral rapamycin is a promising treatment in these extensive and morbidity‐causing cases.

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Bibliographic Details
Published inClinical and experimental dermatology Vol. 47; no. 1; pp. 180 - 182
Main Authors Pérez‐Feal, P., Moreiras‐Arias, N., Buján‐Bonino, C., Suárez‐Peñaranda, J. M., Fernández‐Redondo, V.
Format Journal Article
LanguageEnglish
Published England Oxford University Press 01.01.2022
Subjects
Administration, Oral
Adolescent
Antibiotics, Antineoplastic - therapeutic use
Humans
Lymphangioma
Lymphangioma - complications
Lymphangioma - drug therapy
Lymphangioma - pathology
Male
Morbidity
Noonan Syndrome - complications
Noonan's syndrome
Penis - pathology
Rapamycin
Scrotum - pathology
Sirolimus - therapeutic use
Skin Neoplasms - complications
Skin Neoplasms - drug therapy
Skin Neoplasms - pathology
Treatment Outcome
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Summary:Lymphangioma is a known, but rare manifestation of Noonan syndrome. We present the case of disseminated and circumscribed cutaneous lymphangiomas in the context of Noonan syndrome. Oral rapamycin is a promising treatment in these extensive and morbidity‐causing cases.
Bibliography:Conflict of interest: the authors declare that they have no conflicts of interest.
SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:0307-6938
1365-2230
DOI:10.1111/ced.14873