The interaction between obesity and visceral hypersensitivity

• Published in: Journal of gastroenterology and hepatology Vol. 38; no. 3; pp. 370 - 377
• Main Authors: Yanping, Wu, Gao, Xuefen, Cheng, Yizun, Liu, Mi, Liao, Siyu, Zhou, Jing, Hao, Jiaming, Jiang, Gemeng, Lu, Yixuan, Qu, Tianyao, Qin, Bin, Cheng, Yan
• Format: Journal Article
• Language: English
• Published: Australia Wiley Subscription Services, Inc 01.03.2023
• Subjects: Adipose tissue; Cardiovascular diseases; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - metabolism; Humans; Hypersensitivity; Inflammation; Intestinal Mucosa - metabolism; Intestine; Intestines; Irritable bowel syndrome; Irritable Bowel Syndrome - metabolism; Metabolic disorders; Microbiota; Nerve endings; Obesity; Vitamin D; Vitamin deficiency; microbiota; inflammation; irritable bowel syndrome; vitamin D; obesity

Obesity has been a worldwide problem associated with numerous chronic diseases such as cardiovascular disease, type 2 diabetes, and metabolic disorders. It may also play a role in visceral hypersensitivity, contributing to irritable bowel syndrome. (i) Adipose tissue secretes various inflammatory me...