Mouth examination performance by children's parents and by adolescents in Fanconi anemia

• Published in: Pediatric blood & cancer Vol. 64; no. 11
• Main Authors: Pivovar, Allana, Furquim, Camila Pinheiro, Bonfim, Carmem, Torres‐Pereira, Cassius Carvalho
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.11.2017
• Subjects: Adolescent; Adolescents; Anemia; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - etiology; Caregivers; Child; Child, Preschool; Children; Cross-Sectional Studies; Fanconi anemia; Fanconi Anemia - complications; Fanconi syndrome; Female; Follow-Up Studies; Health risks; Hematology; Humans; Infant; Male; Mouth; Mouth - pathology; Mouth Neoplasms - diagnosis; Mouth Neoplasms - etiology; Mucosa; Oncology; Oral cancer; Oral squamous cell carcinoma; Parents; Parents & parenting; Pediatrics; Prognosis; screening; Squamous cell carcinoma; surveillance; Teenagers; screening; surveillance; Fanconi anemia; oral cancer
• ISSN: 1545-5009; 1545-5017
• DOI: 10.1002/pbc.26622

Background Fanconi anemia (FA) is a rare genetic syndrome characterized by increased risk of developing malignant neoplasms, particularly oral squamous cell carcinoma. This study aims to ascertain the extent to which adolescents and guardians/parents of children with FA are aware of their oral cancer risks and assess their ability to perform mouth examination (ME). Procedure A cross‐sectional study was conducted among patients with FA (between 6 and 16 years) and their parents. A total of 45 patients, 19 children and 26 adolescents, participated in the study. Among children less than 12 years of age, caregivers performed ME and adolescents between 12 and 16 years of age performed mouth self‐examination (MSE). All parents were given a self‐reporting questionnaire to collect sociodemographic data, information about health‐related behaviors, and oral cancer awareness. Performance was evaluated using criteria for mucosal visualization and retracting ability. Subsequently, a dentist clinically examined all patient participants. Results Performance evaluation indicated that the examination quality was unsatisfactory in both groups. Statistical significance was found between ability to perform ME by marital status (P < 0.036), where divorced parents had more difficulty performing ME than nondivorced parents. Conclusion Oral mucosa surveillance performed by parents and adolescents seems to be inaccurate. However, as an oral examination is a relatively inexpensive form of secondary prevention, it merits attention to teaching the technique to patients with FA and their caregivers.