Overview of smoking and all cancers

Tobacco consumption has been clearly implicated in the causation of many cancer types, with irrefutable evidence to support the association in multiple organ systems. Tobacco cessation leads to reduced cancer risk and improved survival of those under treatment for their already established cancers....

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Bibliographic Details
Published inThe Medical clinics of North America Vol. 88; no. 6; p. 1655
Main Authors Levitz, Jason S, Bradley, Thomas P, Golden, Anne L
Format Journal Article
LanguageEnglish
Published United States 01.11.2004
Subjects
Female
Humans
Male
Neoplasms - etiology
Neoplasms - physiopathology
Nicotiana - adverse effects
Nicotiana - chemistry
Ribonucleotide Reductases - antagonists & inhibitors
Smoking - adverse effects
Tars - adverse effects
Tobacco Smoke Pollution - adverse effects
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Summary:Tobacco consumption has been clearly implicated in the causation of many cancer types, with irrefutable evidence to support the association in multiple organ systems. Tobacco cessation leads to reduced cancer risk and improved survival of those under treatment for their already established cancers. As understanding of the mechanisms by which tobacco products cause cancer increases, clinicians may be able to identify those at highest risk for tobacco-related malignancies and allow for more focused interventions toward risk reduction among current tobacco users. This article reviews the carcinogens present in tobacco products, the mechanisms by which tobacco causes cancer, and the various tumor types causally related to tobacco use.
ISSN:0025-7125
DOI:10.1016/j.mcna.2004.07.005