Adaptive control of left ventricular bypass assist devices

• Published in: IEEE transactions on automatic control Vol. 30; no. 4; pp. 322 - 329
• Main Authors: McInnis, B., Zhong-Wei Guo, Po Lu, Jiun-Chung Wang
• Format: Journal Article
• Language: English
• Published: New York, NY IEEE 01.04.1985; Institute of Electrical and Electronics Engineers
• Subjects: Adaptive control; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Artificial heart; Automatic control; Biological and medical sciences; Blood pressure; Cardiology; Circulatory system; Control systems; Electrocardiography; Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care; Intensive care medicine; Medical sciences; Pressure control; Voltage; Intensive cardiocirculatory care; Cardiocirculatory assistance; Bypass; Implanted; Cardiovascular disease; Apparatus; Pump; Left ventricle; Biomedical engineering
• ISSN: 0018-9286; 1558-2523
• DOI: 10.1109/TAC.1985.1103950

This paper presents a computer-based adaptive control system for left ventricular bypass assist devices consisting of air driven diaphragm pumps. The system provides for 1) synchronization of pumping with ECG signals and 2) control of atrial pressure at desired levels. The system design includes an adaptive control algorithm which is a self-tuning PID-controller based on pole placement. The performance of the system has been demonstrated by in vitro experiments_ on a mock circulatory system. When there is an increase in atrial pressure, the system responds with an increase in stroke volume. Following major changes in the circulatory system, the control algorithm retunes itself and restores the system to the desired state.