Current devices and interventions in mitral regurgitation

• Published in: Herz Vol. 46; no. 5; pp. 419 - 428
• Main Authors: Koell, Benedikt, Kalbacher, Daniel, Lubos, Edith
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer Medizin 01.10.2021; Springer Nature B.V
• Subjects: Aging; Asymptomatic; Cardiology; Cardiovascular disease; Catheters; Etiology; Heart; Heart valves; Internal Medicine; Intervention; Main Topic; Medicine; Medicine & Public Health; Mitral valve; Mortality; Regurgitation; Stress concentration; Surgery; Therapy; Vascular implants; Structural heart disease; Katheterinterventionelle Therapie; Kathetergestützter Mitralklappenersatz; Transcatheter mitral valve repair; Transcatheter mitral valve implantation; Strukturelle Herzerkrankungen; Kathetergestützte Mitralklappenrekonstruktion; Mitral valve insufficiency; Transcatheter therapy; Mitralklappeninsuffizienz
• ISSN: 0340-9937; 1615-6692
• DOI: 10.1007/s00059-021-05055-w

Mitral regurgitation (MR) is the most common valvular disease. With a rising incidence in older age, the prevalence of relevant comorbidities inevitably increases. Considering the constantly aging population with high surgical risk, transcatheter therapy of MR is gaining increasing importance. Interventional therapy of either primary or secondary MR represents an alternative to pure drug or surgical therapy. With mitral valve transcatheter edge-to-edge repair, a well-established treatment has evolved in the past two decades. In addition, direct or indirect annuloplasty and ultimately transcatheter mitral valve implantation further expand the armamentarium. The current broad spectrum of interventional therapy options allows for patient-oriented therapy individually targeting different MR pathologies. This review discusses the current landscape of transcatheter therapies for relevant MR.