The bactericidal effect of far-UVC on ESBL-producing Escherichia coli

• Published in: American journal of infection control Vol. 50; no. 11; pp. 1268 - 1270
• Main Authors: Fukuda, Soichiro, Nishikawa, Jun, Kobayashi, Yuki, Okabe, Yumi, Fujii, Tomohiro, Kubota, Naoto, Otsuyama, Ken-Ichiro, Tsuneoka, Hidehiro, Hashimoto, Shinichi, Suehiro, Yutaka, Yamasaki, Takahiro, Takami, Taro
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.11.2022
• Subjects: Bactericidal effect; Escherichia coli (E. coli); Extended-spectrum beta-lactamase (ESBL); Far-ultraviolet C; Extended-spectrum beta-lactamase (ESBL); Far-ultraviolet C; Escherichia coli (E. coli); Bactericidal effect
• ISSN: 0196-6553; 1527-3296
• DOI: 10.1016/j.ajic.2022.04.012

•Extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease.•The bactericidal effect of far- ultraviolet C (far-UVC) on the ESBL-producing Escherichia coli (E. coli) was shown.•Irradiation with far- UVC may be effective in preventing infection by ESBL-producing E. coli. Because extended-spectrum beta-lactamase (ESBL) infections can cause life-threatening disease and effective treatments need to be developed, we examined the bactericidal effect of far-ultraviolet C (far-UVC) light therapy on ESBL-producing Escherichia coli (E. coli). The bactericidal effect on 2 types of ESBL-producing E. coli was the same as that on the wild strain although the results of drug resistance tests varied among these strains. We believe that irradiation with far-UVC is effective in preventing infection by ESBL-producing E. coli in health care settings.