Research on synthesis and property of nano-textured Sc2O3-MgO efficient antibacterial agents

• Published in: Journal of biological inorganic chemistry Vol. 28; no. 3; pp. 329 - 343
• Main Authors: Wang, Ying, Liu, Yanjing, Li, Xiyue, Liu, Yuezhou, Wang, Fuming, Huang, Yaping, Du, Bing, Qian, Yongfang, Lv, Lihua
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.04.2023; Springer Nature B.V
• Subjects: Antibacterial activity; Antibacterial agents; Biochemistry; Biomedical and Life Sciences; Life Sciences; Microbiology; Original Paper; Sc; Nano-MgO; Nanotextures; Antibacterial property; Ion doping
• ISSN: 1432-1327; 0949-8257; 1432-1327
• DOI: 10.1007/s00775-023-01995-2

In order to obtain the inorganic efficient antibacterial agents, the means of ion doping and morphology construction in this research are used to enhance the antibacterial property of nano-MgO, which is according to the “oxidative damage mechanism” and “contact mechanism”. In this work, the nano-textured Sc 2 O 3 -MgO are synthesized by doping Sc 3+ in nano-MgO lattice through calcining at 600 °C. When the Sc 3+ content reaches 10%, the nanotextures on the powders surface are pretty clearly visible and uniform, and the specific surface area and the oxygen vacancy are ideal, so that the 10% Sc 3+ -doped powders (SM-10) has the excellent antibacterial property against E. coli and S. aureus (MBC = 0.03 mg/mL). The efficient antibacterial agents in this research have a better antibacterial effect than the 0% Sc 3+ -doped powders (SM-0, MBC = 0.20 mg/mL) and the commercial nano-MgO (CM, MBC = 0.40 mg/mL), which have application prospects in the field of antibacterial.