The Efficacy and Safety of Laparoscopic Single-Anastomosis Duodeno-ileostomy with Sleeve Gastrectomy (SADI-S) in Mid- and Long-Term Follow-Up: a Systematic Review

• Published in: Obesity surgery Vol. 33; no. 12; pp. 4070 - 4079
• Main Authors: Esparham, Ali, Roohi, Samira, Ahmadyar, Soheil, Dalili, Amin, Moghadam, Hengameh Anari, Torres, Antonio José, Khorgami, Zhamak
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.12.2023; Springer Nature B.V
• Subjects: Body mass index; Diabetes; Gastrointestinal surgery; Laparoscopy; Medicine; Medicine & Public Health; Metabolic disorders; Obesity; Ostomy; Review; Sleep apnea; Surgery; Surgical techniques; Systematic review; Weight control; Single-anastomosis duodeno-ileal bypass; One-anastomosis duodenal switch; Single-anastomosis duodeno-ileostomy; Bariatric surgery; Duodenal switch; Long-term; Mid-term; SADI-S; SIPS
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-023-06846-2

This systematic review of 10 studies aimed to investigate the mid- and long-term results of duodeno-ileostomy with sleeve gastrectomy (SADI-S) according to the PRISMA guideline. Related articles, which reported outcomes of laparoscopic SADI-S with follow-up ≥ 3 years, were selected and analyzed. The percentage of excess weight loss (EWL) was 70.9–88.7%, and 80.4% at 6, and 10 years, respectively. The more common late complications were malabsorption (6.3%) and gastroesophageal reflux disease (GERD) (3.6%). The remission rates of hypertension, diabetes, GERD, obstructive sleep apnea, and dyslipidemia were 62.9%, 81.3%, 53.2%, 60.9%, and 69.7%, respectively. In conclusion, SADI-S is a safe and effective surgical technique with durable weight loss and a high rate of comorbidity resolution in mid and long term. Graphical Abstract