Ni/Al2O3: Catalyzed Carbonylative Homocoupling of Aryl Iodides for the Synthesis of Symmetrical Diaryl Ketone Using Co2(CO)8 as CO Surrogate

• Published in: Catalysis letters Vol. 154; no. 4; pp. 1440 - 1450
• Main Authors: Mahajan, Vijay P., Kolekar, Yuvraj A., Bhanage, Bhalchandra M.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2024; Springer Nature B.V
• Subjects: acetates; Acids; Aluminum oxide; Aromatic compounds; carbon dioxide; Carbon monoxide; Carbonyls; Catalysis; Catalysts; catalytic activity; Chemical reactions; Chemical synthesis; Chemistry; Chemistry and Materials Science; Coupling; Electron microscopy; energy-dispersive X-ray analysis; Inductively coupled plasma; Industrial Chemistry/Chemical Engineering; Iodides; Ketones; Nanoparticles; Nickel; Optical emission spectroscopy; Organometallic Chemistry; Palladium; Physical Chemistry; Recycling; Scanning electron microscopy; sodium borohydride; spectroscopy; Thermogravimetric analysis; thermogravimetry; toxicity; transmission electron microscopy; X-ray diffraction; Diaryl ketone; Nickel; Al; Carbonylative homo-coupling; CO surrogate; O
• ISSN: 1011-372X; 1572-879X
• DOI: 10.1007/s10562-023-04430-y

This work reports the carbonylative homo-coupling reactions for the synthesis of diaryl ketones using nickel supported on Al 2 O 3 . A heterogeneous Ni/Al 2 O 3 catalyst was prepared from the reaction of nickel acetate and aluminum oxide in the presence of sodium borohydride. The catalyst was employed as a heterogeneous catalyst for carbonylative homo-coupling of aryl iodides under carbon monoxide gas-free conditions. Co 2 (CO) 8 was used as the carbon monoxide source and the desired symmetrical diaryl ketones were achieved in good to excellent yields. Moreover, the catalyst was reused for up to five consecutive cycles without significant loss of activity. The Ni/Al 2 O 3 catalyst was characterized by inductively coupled plasma optical emission spectroscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and thermogravimetric analysis. The use of Co 2 (CO) 8 as a cheap, less toxic, and solid surrogate is an additional advantage over the current protocol. Graphical Abstract