Clinical and imaging features of spinal extradural arachnoid cysts: a retrospective study of 50 cases

• Published in: Neuroradiology Vol. 64; no. 12; pp. 2409 - 2416
• Main Authors: Ahmed, Ahmed K., Anisetti, Bhrugun, Huynh, Thien, Agarwal, Amit, Gupta, Vivek, Desai, Amit, Singh, Rahul, Vibhute, Prasanna
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2022; Springer Nature B.V
• Subjects: Arachnoid; Back pain; Bone mass; Bone remodeling; Brain diseases; Cysts; Demography; Imaging; Medical imaging; Medicine; Medicine & Public Health; Neurology; Neuroradiology; Neurosciences; Neurosurgery; Pain; Radiology; Remission; Spinal Neuroradiology; Spine (thoracic); Statistical analysis; Arachnoid cyst; Extradural cyst; MRI; Spine
• ISSN: 0028-3940; 1432-1920; 1432-1920
• DOI: 10.1007/s00234-022-03042-4

Purpose Spinal extradural arachnoid cysts (SEDACs) are thought to arise from leakage of CSF through a spinal dural defect. This study investigates the demographics and imaging spectrum of SEDACs at our academic institution and compares them with those reported in the literature. Methods Fifty cases with documented MRI diagnosis of SEDAC, Nabors criteria type I meningeal cyst (MC), were identified from retrospective review of imaging records between 1999 and 2020. Patient demographics, presenting symptoms, cyst characteristics, and management outcomes were studied. Statistical analysis was performed to determine associations between maximum cyst size and presenting symptoms along with other imaging findings. Results In all 50 subjects, SEDACs were solitary (single) and sporadic (non-familial). The majority were incidental (62%), located posteriorly (92%) and laterally (80%) in the thoracic and thoracolumbar regions (34%, 30%). They were associated with mild mass effect upon the thecal sac (50%) and bone remodeling (92%). Among symptomatic SEDACs, back pain and radiculopathy were the most reported (68%). Larger cysts were located caudally in the spinal canal, and were associated with greater thecal mass effect, bone remodeling, and septations. Four out of six subjects who underwent surgical management had complete or partial remission. One had cyst recurrence. Conclusion In this largest series of SEDACs, most were discovered incidentally, stable over time, and located in the thoracic spine dorsal to the thecal sac. When symptomatic, back pain and radiculopathy were the most common presenting symptoms. Treatment with complete surgical excision may yield the best results for symptomatic lesions.