Hemophagocytic lymphohistiocytosis in children with visceral leishmaniasis

Acquired hemophagocytic lymphohistiocitosis (HLH) syndrome can be a complication of visceral leishmaniasis (VL). A multicenter prospective study was conducted to determine the frequency of HLH syndrome in children with VL. Twenty-four children with VL were identified, and 10 (41%) developed HLH synd...

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Bibliographic Details
Published inThe Pediatric infectious disease journal Vol. 34; no. 6; p. 667
Main Authors Blázquez-Gamero, Daniel, Domínguez-Pinilla, Nerea, Chicharro, Carmen, Negreira, Sagrario, Galán, Pilar, Pérez-Gorricho, Beatriz, Calvo, Cristina, Prieto, Luis, De la Parte, María, Otheo, Enrique, Vivanco, Jose Luis, Ruiz-Contreras, Jesús
Format Journal Article
LanguageEnglish
Published United States 01.06.2015
Subjects
Adolescent
Child
Child, Preschool
Female
Humans
Infant
Infant, Newborn
Leishmaniasis, Visceral - complications
Lymphohistiocytosis, Hemophagocytic - epidemiology
Lymphohistiocytosis, Hemophagocytic - pathology
Male
Prospective Studies
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Summary:Acquired hemophagocytic lymphohistiocitosis (HLH) syndrome can be a complication of visceral leishmaniasis (VL). A multicenter prospective study was conducted to determine the frequency of HLH syndrome in children with VL. Twenty-four children with VL were identified, and 10 (41%) developed HLH syndrome. VL should be ruled out in all children with HLH criteria living in or coming from endemic areas.
ISSN:1532-0987
DOI:10.1097/INF.0000000000000685