Understanding and Targeting the Colon Cancer Pathogenesis: A Molecular Perspective

• Published in: Brazilian Journal of Pharmaceutical Sciences Vol. 58
• Main Author: Khan, Imran
• Format: Journal Article
• Language: English
• Published: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 01.01.2022; Universidade de São Paulo
• Subjects: Colon cancer; Hedgehog; Molecular targets; Notch; PHARMACOLOGY & PHARMACY; WNT/β-catenin; Molecular targets; WNT/β-catenin; Hedgehog; Colon cancer; Notch

Abstract Colorectal cancer (CRC) one of the leading cause of cancer-related deaths worldwide. With the presently available knowledge on CRC, it is understood that the underlying is a complex process. The complexity of CRC lies in aberrant activation of several cellular signaling pathways that lead t...