Induction of cytochrome P-450 by pregnenolone-16 alpha-carbonitrile in primary monolayer cultures of adult rat hepatocytes and in a cell-free translation system

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Bibliographic Details
Published inThe Journal of biological chemistry Vol. 256; no. 12; pp. 6060 - 6068
Main Authors Elshourbagy, N A, Barwick, J L, Guzelian, P S
Format Journal Article
LanguageEnglish
Published United States 25.06.1981
Subjects
Aminopyrine N-Demethylase - metabolism
Animals
Cell-Free System
Cells, Cultured
Cytochrome P-450 Enzyme System - biosynthesis
Enzyme Induction - drug effects
Ethylmorphine-N-Demethylase - metabolism
Female
Immunodiffusion
Liver - enzymology
Pregnenolone Carbonitrile - pharmacology
Protein Biosynthesis
Rats
RNA, Messenger - metabolism
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ISSN:0021-9258
DOI:10.1016/S0021-9258(19)69128-3