Goat-mouse hybridomas secreting goat immunoglobulins

Monoclonal antibodies specific for an allotypic marker of goat IgG2 were used to select goat-mouse hybrid cells secreting goat IgG2. Four of these hybrid cell clones continued to synthesize goat IgG2 (5-15 micrograms/ml) for over eight months. They will be used to study goat IgG gene regulation.

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Bibliographic Details
Published inHybridoma Vol. 9; no. 2; p. 149
Main Authors Capparelli, R, Del Sorbo, G, Iannelli, D
Format Journal Article
LanguageEnglish
Published United States 01.04.1990
Subjects
Animals
Cell Fusion
Cell Line
Female
Goats - immunology
Hybridomas - immunology
Immunoglobulin G - secretion
Lymphocytes
Mice
Multiple Myeloma
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Summary:Monoclonal antibodies specific for an allotypic marker of goat IgG2 were used to select goat-mouse hybrid cells secreting goat IgG2. Four of these hybrid cell clones continued to synthesize goat IgG2 (5-15 micrograms/ml) for over eight months. They will be used to study goat IgG gene regulation.
ISSN:0272-457X
DOI:10.1089/hyb.1990.9.149