HIV establishes an early foothold

The weeks following HIV acquisition are a critical time when the virus causes significant immunological damage and establishes long-term latent reservoirs. A recent study in Immunity by Gantner et al. uses single-cell analysis to explore these key early infection events, providing insights into earl...

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Bibliographic Details
Published inCell host & microbe Vol. 31; no. 4; pp. 571 - 573
Main Authors Moran, Jose A., Marsden, Matthew D.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 12.04.2023
Subjects
CD4-Positive T-Lymphocytes
HIV Infections
Humans
Virus Latency
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Summary:The weeks following HIV acquisition are a critical time when the virus causes significant immunological damage and establishes long-term latent reservoirs. A recent study in Immunity by Gantner et al. uses single-cell analysis to explore these key early infection events, providing insights into early HIV pathogenesis and reservoir formation. The weeks following HIV acquisition are a critical time when the virus causes significant immunological damage and establishes long-term latent reservoirs. A recent study in Immunity by Gantner et al. uses single-cell analysis to explore these key early infection events, providing insights into early HIV pathogenesis and reservoir formation.
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ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2023.03.012