False-positive Aspergillus antigenemia due to blood product conditioning fluids

The presence of Aspergillus antigens in blood transfusion components from different manufacturers was analyzed. Galacomannans were found in transfused patients, pooled platelet concentrates, fresh frozen plasma, and packed red cells collected using Fresenius Kabi bags. Galacomannans were also found...

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Bibliographic Details
Published inClinical infectious diseases Vol. 55; no. 4; pp. e22 - e27
Main Authors Martín-Rabadán, Pablo, Gijón, Paloma, Alonso Fernández, Roberto, Ballesteros, Mónica, Anguita, Javier, Bouza, Emilio
Format Journal Article
LanguageEnglish
Published United States Oxford University Press 15.08.2012
Subjects
Aged
Anticoagulants
Antigens
Antigens, Fungal - blood
Aspergillosis - blood
Aspergillosis - diagnosis
Aspergillus - isolation & purification
Blood platelets
Blood products
Cells
Cytomegalovirus Infections - blood
Cytomegalovirus Infections - diagnosis
False Positive Reactions
Female
Fungemia - blood
Fungemia - diagnosis
Humans
Mannans - blood
Mold
Platelet Transfusion - adverse effects
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Summary:The presence of Aspergillus antigens in blood transfusion components from different manufacturers was analyzed. Galacomannans were found in transfused patients, pooled platelet concentrates, fresh frozen plasma, and packed red cells collected using Fresenius Kabi bags. Galacomannans were also found in blood collection anticoagulant and platelet additive solution from this manufacturer.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/cis493