Transferrin C subtypes and spontaneous abortion

The transferrin C subtypes were studied in relation to spontaneous abortion and a number of different genetic markers and traits. Among mothers with a history of spontaneous abortion an increased frequency of the C2 gene and especially of the C2 type was found. A correlation was found between the ma...

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Bibliographic Details
Published inHuman heredity Vol. 30; no. 5; p. 316
Main Authors Beckman, G, Beckman, L, Sikström, C
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1980
Subjects
Abortion, Habitual - genetics
Adult
Alkaline Phosphatase - genetics
Female
Gene Frequency
Humans
Infant, Newborn
Polymorphism, Genetic
Pregnancy
Selection, Genetic
Transferrin - genetics
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Summary:The transferrin C subtypes were studied in relation to spontaneous abortion and a number of different genetic markers and traits. Among mothers with a history of spontaneous abortion an increased frequency of the C2 gene and especially of the C2 type was found. A correlation was found between the maternal C2 type and the placental alkaline phosphatase variant F, which previously has been shown to be associated with spontaneous abortion. The mechanism behind the intrauterine selection implied is unlikely to be immunological incompatibility between mother and fetus. No association was found with ABO and Rh blood groups, Hp and Gc serum groups, the pregnancy zone protein (PZ), red cell acid phosphatase types and birth weight.
ISSN:0001-5652
DOI:10.1159/000153149