Friends with Benefits: Microenvironmental NRG1β and HGF Mediate HER2-Targeted Resistance in L-HER2+ and HER2E Breast Cancer

Watson et al. use microenvironment microarrays to assess how extrinsic signals within the tumor microenvironment influence HER2++ breast cancer resistance to the HER2-targeted tyrosine kinase inhibitor lapatinib. Watson et al. use microenvironment microarrays to assess how extrinsic signals within t...

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Bibliographic Details
Published inCell systems Vol. 6; no. 3; pp. 268 - 270
Main Authors Crist, Sarah B., Ghajar, Cyrus M.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 28.03.2018
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Summary:Watson et al. use microenvironment microarrays to assess how extrinsic signals within the tumor microenvironment influence HER2++ breast cancer resistance to the HER2-targeted tyrosine kinase inhibitor lapatinib. Watson et al. use microenvironment microarrays to assess how extrinsic signals within the tumor microenvironment influence HER2++ breast cancer resistance to the HER2-targeted tyrosine kinase inhibitor lapatinib.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:2405-4712
2405-4720
DOI:10.1016/j.cels.2018.03.005