Aryl acyl peroxides for visible-light induced decarboxylative arylation of quinoxalin-2(1)-ones under additive-, metal catalyst-, and external photosensitizer-free and ambient conditions

• Published in: Green chemistry : an international journal and green chemistry resource : GC Vol. 23; no. 1; pp. 374 - 378
• Main Authors: Xie, Long-Yong, Peng, Sha, Yang, Li-Hua, Peng, Cun, Lin, Ying-Wu, Yu, Xianyong, Cao, Zhong, Peng, Yu-Yu, He, Wei-Min
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 18.01.2021; Royal Society of Chemistry
• Subjects: Acetic acid; Aromatic compounds; arylation; Catalysts; Chemistry; Chemistry, Multidisciplinary; Ethyl acetate; Green & Sustainable Science & Technology; Green chemistry; Light; lighting; Peroxides; photosensitizing agents; Physical Sciences; regioselectivity; Science & Technology; Science & Technology - Other Topics; MILD; FUNCTIONALIZATION; QUINOXALINONES; QUINOXALIN-2(H)-ONES; C-H ARYLATION; C3-DIFLUOROARYLMETHYLATION; ACIDS; BOND; SALTS; TRIFLUOROMETHYLATION
• ISSN: 1463-9262; 1463-9270; 1463-9270
• DOI: 10.1039/d0gc02844d

Aryl radicals were generated for the first time from cheap and easily available aryl acyl peroxides in eco-friendly ethyl acetate under ambient conditions and visible-light illumination in the absence of any additive, metal catalyst, or external photosensitizer. The present arylation of quinoxalin-2(1 H )-ones was chemo- and regioselective, and provided good access to various 3-arylquinoxalin-2(1 H )-ones. Aryl radicals were generated for the first time from aryl acyl peroxides in ethyl acetate under ambient conditions and visible-light illumination in the absence of any additive, metal catalyst, or external photosensitizer.