Hemagglutinating properties of CELO [chicken-embryo-lethal-orphan virus], an oncogenic avian adenovirus

Chicken-embryo-lethal-orphan (CELO) virus, Phelps strain, agglutinated erythrocytes at 37 C. The hemagglutinating activity, which is a function of complete and incomplete virus particles, was sensitive to heat but not to pH. The soluble components of the virus were similar in sedimentation character...

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Published inAvian diseases Vol. 19; no. 4; pp. 761 - 772
Main Authors el-Mishad, A.M, McCormick, K.J, Stenback, W.A, Yates, V.J, Trentin, J.J
Format Journal Article
LanguageEnglish
Published United States 01.10.1975
Subjects
Adenoviridae - immunology
animal diseases
animal health
Aviadenovirus - analysis
Aviadenovirus - immunology
Aviadenovirus - ultrastructure
Erythrocytes - immunology
Erythrocytes - ultrastructure
Hemagglutination, Viral
Hemagglutinins, Viral
Oncogenic Viruses - analysis
Oncogenic Viruses - immunology
Oncogenic Viruses - ultrastructure
Temperature
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Summary:Chicken-embryo-lethal-orphan (CELO) virus, Phelps strain, agglutinated erythrocytes at 37 C. The hemagglutinating activity, which is a function of complete and incomplete virus particles, was sensitive to heat but not to pH. The soluble components of the virus were similar in sedimentation characteristics to those obtained from human adenovirus type 1. The effects of chemical and physical agents on CELO hemagglutinin, CELO infectivity, and red-cell receptors suggested that the last were protein in nature and that cell-virus attachment was mediated by amino groups on the virion. The attachment of virus to red blood cells via the penton projection was demonstrated by electron microscopy.
Bibliography:L
L73
ISSN:0005-2086
1938-4351
DOI:10.2307/1589189