A case of fulminant pneumococcus meningoencephalitis progressing with white matter involvement despite two doses of conjugated pneumococcus vaccine

Streptococcus pneumonia is a cause of serious mortality and morbidity, especially among small children. However, currently, it causes lower rates of invasive infections due to successful vaccination programs Case. We report an exceptional case of a 6-month-old child with meningoencephalitis caused b...

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Bibliographic Details
Published inTurkish journal of pediatrics Vol. 62; no. 6; pp. 1058 - 1063
Main Authors Azapağası, Ebru, Kendirli, Tanıl, Tuncer, Gökçen Öz, Özcan, Serhan, Özdemir, Halil, Fitöz, Suat, İnce, Erdal
Format Journal Article
LanguageEnglish
Published Turkey Hacettepe University Faculty of Medicine 01.11.2020
Subjects
Bacterial infections
Blood
Children & youth
Consciousness
Encephalitis
Hearing loss
Hydrocephalus
Magnetic resonance imaging
Meningitis
Morbidity
Mortality
Pediatrics
Pneumonia
Streptococcus infections
Vaccines
serotype 19F
meningoencephalitis
streptococcus pneumoniae
meningitis
pneumococcal conjugate vaccine
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Summary:Streptococcus pneumonia is a cause of serious mortality and morbidity, especially among small children. However, currently, it causes lower rates of invasive infections due to successful vaccination programs Case. We report an exceptional case of a 6-month-old child with meningoencephalitis caused by Streptococcus pneumonia despite the administration of two doses of pneumococcal conjugate vaccine (PCV). Meningitis progressed rapidly and led to widespread damage in parenchymal brain tissue with the emergence of fulminant meningoencephalitis. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed widespread brain lesions, suggesting extensive parenchymal injury. Such diffuse white matter lesions among pediatric patients with Streptococcus pneumonia meningoencephalitis despite two doses of PCV have not been reported previously.
ISSN:0041-4301
2791-6421
DOI:10.24953/turkjped.2020.06.018