Esophageal Eosinophilia Treated With Long-Duration Proton Pump Inhibitor Therapy

We present a case of proton pump inhibitor-responsive eosinophilic esophagitis (PPI-REE) in a patient with severe dysphagia and markedly elevated baseline esophageal eosinophilia that was previously deemed unresponsive to PPI. Upon reintroduction to PPI therapy with monthly endoscopy and dilation ov...

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Bibliographic Details
Published inACG case reports journal Vol. 3; no. 2; pp. 95 - 97
Main Authors DiGiovanni, Ernest L, Champeaux, Anne L, Arroyo, May R, Richter, Joel E
Format Journal Article
LanguageEnglish
Published United States American College of Gastroenterology 01.01.2016
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Case Report
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Summary:We present a case of proton pump inhibitor-responsive eosinophilic esophagitis (PPI-REE) in a patient with severe dysphagia and markedly elevated baseline esophageal eosinophilia that was previously deemed unresponsive to PPI. Upon reintroduction to PPI therapy with monthly endoscopy and dilation over the course of 4 months, the patient improved clinically and resolved her mucosal eosinophilia. Our case suggests that a longer duration of PPI therapy may be required for histologic improvement, especially in patients with very high mucosal eosinophil count.
ISSN:2326-3253
2326-3253
DOI:10.14309/crj.2016.11