Medicaid expansion and racial disparity in timely multidisciplinary treatment in muscle invasive bladder cancer

• Published in: JNCI : Journal of the National Cancer Institute Vol. 115; no. 10; pp. 1188 - 1193
• Main Authors: Jiang, Changchuan, Perimbeti, Stuthi, Deng, Lei, Xing, Jiazhang, Chatta, Gurkamal S, Han, Xuesong, Gopalakrishnan, Dharmesh
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 09.10.2023; Oxford Publishing Limited (England)
• Subjects: Bladder; Bladder cancer; Cancer; Cancer therapies; Chemotherapy; Comorbidity; Diagnosis; Government programs; Inequality; Invasiveness; Medicaid; Methyl isobutyl carbinol; Minority & ethnic groups; Muscles; Patients; Race factors; Racial differences; Urological surgery
• ISSN: 0027-8874; 1460-2105
• DOI: 10.1093/jnci/djad112

Abstract Background Multidisciplinary cancer care (neoadjuvant chemotherapy followed by radical cystectomy or trimodality therapy) is crucial for outcome of muscle-invasive bladder cancer (MIBC), a potentially curable illness. Medicaid expansion through Affordable Care Act (ACA) increased insurance coverage especially among patients of racial minorities. This study aims to investigate the association between Medicaid expansion and racial disparity in timely treatment in MIBC. Methods This quasi-experimental study analyzed Black and White individuals aged 18-64 years with stage II and III bladder cancer treated with neoadjuvant chemotherapy followed by radical cystectomy or trimodality therapy from National Cancer Database 2008-2018. Primary outcome was timely treatment started within 45 days following cancer diagnosis. Racial disparity is the percentage-point difference between Black and White patients. Patients in expansion and nonexpansion states were compared using difference-in-differences and difference-in-difference-in-differences analyses, controlling for age, sex, area-level income, clinical stage, comorbidity, metropolitan status, treatment type, and year of diagnosis. Results The study included 4991 (92.3% White, n = 4605; 7.7% Black, n = 386) patients. Percentage of Black patients who received timely care increased following the ACA in Medicaid expansion states (54.5% pre-ACA vs 57.4% post-ACA) but decreased in nonexpansion states (69.9% pre-ACA vs 53.7% post-ACA). After adjusting covariates, Medicaid expansion was associated with a net 13.7 percentage-point reduction of Black–White patient disparity in timely receipt of MIBC treatment (95% confidence interval = 0.5% to 26.8%; P < .01). Conclusions Medicaid expansion was associated with statically significant reduction in racial disparity between Black and White patients in timely multidisciplinary treatment for MIBC.