Evaluation of ELISA in the diagnosis of Yersinia enterocolitica diarrhoea in children

In a series of acute gastroenteritis in children, including 2 bacteriologically confirmed cases of Yersinia enterocolitica infection, paired sera from 286 patients were studied for the presence of Y. enterocolitica 0:3 and 0:9 antibodies, using an enzyme-linked immunosorbent assay (ELISA). In the 2...

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Published inActa pathologica et microbiologica Scandinavica. Section B, Microbiology Vol. 88; no. 3; p. 139
Main Authors Vesikari, T, Granfors, K, Mäki, M, Grönroos, P
Format Journal Article
LanguageEnglish
Published Denmark 01.09.1980
Subjects
Acute Disease
Child
Child, Preschool
Diarrhea - diagnosis
Diarrhea - microbiology
Diarrhea, Infantile - diagnosis
Diarrhea, Infantile - microbiology
Enzyme-Linked Immunosorbent Assay
Humans
Immunoenzyme Techniques
Immunoglobulin A - analysis
Immunoglobulin G - analysis
Immunoglobulin M - analysis
Infant
Yersinia Infections - diagnosis
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Summary:In a series of acute gastroenteritis in children, including 2 bacteriologically confirmed cases of Yersinia enterocolitica infection, paired sera from 286 patients were studied for the presence of Y. enterocolitica 0:3 and 0:9 antibodies, using an enzyme-linked immunosorbent assay (ELISA). In the 2 cases with positive stool culture of Y. enterocolitica 0:3 significant rise was seen in each IgM, IgG and IgA class Y. enterocolitica 0:3 antibodies. There were 6 further cases with elevated anti-Yersinia IgM: these possibly false-positive reactions were distinguished from the confirmed cases of Y. enterocolitica infection by the absence of IgG and IgA antibodies.
ISSN:0105-0656
DOI:10.1111/j.1699-0463.1980.tb02619.x