Chronic eosinophilic perimyositis with persistent myalgias

• Published in: Muscle & nerve Vol. 25; no. 3; pp. 461 - 465
• Main Authors: Zivkovic, Sasa A., Lacomis, David, Clemens, Paula R.
• Format: Journal Article
• Language: English
• Published: New York Wiley Subscription Services, Inc., A Wiley Company 01.03.2002; Wiley
• Subjects: Adult; Biological and medical sciences; Biopsy; Chronic Disease; Diseases of striated muscles. Neuromuscular diseases; Electromyography; Eosinophilia - complications; Eosinophilia - pathology; eosinophilic myositis; eosinophilic perimyositis; Humans; hypereosinophilia; Male; Medical sciences; muscle biopsy; myalgia; Myositis - complications; Myositis - pathology; Neurology; Pain - etiology; Pain - pathology; Human; Pathology; Corticosteroid; Striated muscle disease; Pain; Treatment; Body movement; Myositis; Hemopathy; Electromyography; Myalgia; Eosinophilia
• ISSN: 0148-639X; 1097-4598
• DOI: 10.1002/mus.10054

A 43‐year‐old man with an 8‐year history of hypereosinophilia was evaluated for persistent muscle pain. Methotrexate and corticosteroids were ineffective. Examination, limited by pain even with passive motion, showed only mild weakness. Electromyography and muscle enzymes were normal. A needle muscle biopsy specimen revealed eosinophilic perimyositis. This case illustrates that the diagnosis of eosinophilic perimyositis requires histopathological evaluation, which should be pursued in patients with eosinophilia and persistent myalgia despite normal electromyography and muscle enzymes. © 2002 Wiley Periodicals, Inc. Muscle Nerve 25: 000–000, 2002