F-18 FDG PET/CT as a crucial guide toward optimal treatment planning in a case of postirradiation sarcoma 10 years after primary bone lymphoma of the pelvis

Ten years after chemoradiation for primary lymphoma of the left pelvic bone, a 38-year-old man presented with a 4-month history of gradually increasing pain in his left upper leg and thigh. Initial radiographs and contrast-enhanced magnetic resonance imaging were consistent with recurrent lymphoma,...

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Published inClinical nuclear medicine Vol. 36; no. 7; p. 565
Main Authors de Rooy, Jacky W J, Hambrock, Thomas, Vriens, Dennis, Flucke, Uta E, van der Geest, Ingrid C, van de Luijtgaarden, Addy C, Schreuder, Bart W B, de Geus-Oei, Lioe-Fee
Format Journal Article
LanguageEnglish
Published United States 01.07.2011
Subjects
Adult
Bone Neoplasms - pathology
Bone Neoplasms - radiotherapy
Fluorodeoxyglucose F18
Humans
Lymphoma - pathology
Lymphoma - radiotherapy
Magnetic Resonance Imaging
Male
Pelvic Neoplasms - pathology
Pelvic Neoplasms - radiotherapy
Positron-Emission Tomography
Sarcoma - diagnostic imaging
Sarcoma - etiology
Sarcoma - therapy
Tomography, X-Ray Computed
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Summary:Ten years after chemoradiation for primary lymphoma of the left pelvic bone, a 38-year-old man presented with a 4-month history of gradually increasing pain in his left upper leg and thigh. Initial radiographs and contrast-enhanced magnetic resonance imaging were consistent with recurrent lymphoma, infection, or postirradiation sarcoma. Subsequent F-18 fluorodeoxyglucose positron emission tomography/computed tomography demonstrated a focal area of F-18 fluorodeoxyglucose-avidity within the previously irradiated bone consistent with tumor and the location was confirmed by advanced magnetic resonance imaging techniques and histopathology, thus optimizing treatment planning.
ISSN:1536-0229
DOI:10.1097/RLU.0b013e318217561c