Drug Effect Prediction by Computer

The mass of information available about effects of chemical substances (drugs) on behavioral, biochemical, and physiological systems of living organisms is so extensive as to defy traditional methods of analysis. A procedure that provides automated, computerized searches for patterns among these eff...

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Bibliographic Details
Published inScience (American Association for the Advancement of Science) Vol. 169; no. 3940; pp. 89 - 91
Main Authors Gloye, Eugene E., Marcus, Rudolph J.
Format Journal Article
LanguageEnglish
Published United States American Association for the Advancement of Science 03.07.1970
Subjects
Adrenergics
Analgesics
Antihypertensives
Antipsychotic agents
California
Chemical information
Computers
Dosage
Drug effects
Information search
Information Systems
Narcotics
Pharmacopoeias as Topic
Phenethylamines
Psychopharmacology
Sympathomimetics
California
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Summary:The mass of information available about effects of chemical substances (drugs) on behavioral, biochemical, and physiological systems of living organisms is so extensive as to defy traditional methods of analysis. A procedure that provides automated, computerized searches for patterns among these effects has been developed and has been applied to a data base constructed of medical and chemical information from The Merck Index. One promising result is the development of new hypotheses about mechanisms of drug action.
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.169.3940.89