Usefulness of Elastography for the Evaluation of Subcentimeter Solid Breast Nodules

• Published in: Applied sciences Vol. 11; no. 4; p. 1409
• Main Authors: Guzmán-Aroca, Florentina, Martínez-Paredes, Yésica, de Dios Berná-Serna, Juan, García-Ortega, Ana Azahara, de Dios Berná-Mestre, Juan, Alcaraz, Miguel
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.02.2021
• Subjects: Biopsy; Breast; Breasts; Cysts; Diagnosis; Diagnostic systems; Differential diagnosis; elastography; FDA approval; Histopathology; Lesions; Nodules; S waves; shear wave imaging; Ultrasonic imaging; Ultrasound
• ISSN: 2076-3417; 2076-3417
• DOI: 10.3390/app11041409

The accurate diagnosis of subcentimeter lesions is controversial, and therefore a standardized diagnosis algorithm is needed. The objective of the present work was to study the value of the elastography patterns obtained through the use of the shear wave elastography (SWE) technique with respect to histopathology for the evaluation of nodular breast lesions ≤1 cm. A retrospective study was conducted which included 65 sub-centimeter lesions from 57 patients with an average age of 45.6 ± 11.9. For all the cases, a B-mode ultrasound study, shear wave elastography, and a posterior anatomopathological study were conducted. The lesions had a diameter greater than 7.5 ± 1.7 mm (range: 4–9 mm). Through elastography, the distribution of the patterns was: cyst artifact (n = 13), pattern 1 (n = 4), pattern 2 (n = 31), pattern 3 (n = 13), and pattern 4 (n = 4). Of the 65 lesions, 15 were cysts, 46 were solid benign lesions, and 3 were malignant lesions. The sensitivity of the elastography was 75%, with a specificity of 98.46% and a correct diagnosis in 96.92% of the cases (n = 63). The results from this study show the usefulness of SWE for the evaluation of sub-centimeter breast lesions. In addition, this diagnostic strategy helps with the differential diagnosis between benign and malignant lesions and contributes to the early detection of malignant breast lesions.