Primary extramedullary plasmacytoma of the penis: a case report

Extramedullary plasmacytoma involving the penis is extremely rare. Here, we describe a case of primary extramedullary plasmacytoma of the penis in a 64-year-old man who presented with a palpable penile mass. Nuclear magnetic resonance imaging revealed the presence of a large, round non-encapsulated...

Full description

Saved in:
Bibliographic Details
Published inJapanese journal of clinical oncology Vol. 43; no. 10; pp. 1030 - 1033
Main Authors Wang, Yao, Li, Hong-Yan, Liang, Ting-Ting, Han, Yu-Ping, Wang, Xue-Ju, Wei, Xin, Fan, Li, Wang, Wei-Hua
Format Journal Article
LanguageEnglish
Published England 01.10.2013
Subjects
ADP-ribosyl Cyclase 1 - analysis
Biomarkers, Tumor - analysis
Contrast Media
Diagnosis, Differential
Humans
Immunohistochemistry
Ki-67 Antigen - analysis
Magnetic Resonance Spectroscopy
Male
Membrane Glycoproteins - analysis
Middle Aged
Penile Neoplasms - chemistry
Penile Neoplasms - diagnosis
Penile Neoplasms - pathology
Penile Neoplasms - surgery
Plasmacytoma - chemistry
Plasmacytoma - diagnosis
Plasmacytoma - pathology
Plasmacytoma - surgery
Tomography, X-Ray Computed - methods
Vimentin - analysis
corpora cavernosa
penis
extramedullary plasmacytoma
Online AccessGet full text

Cover

More Information
Summary:Extramedullary plasmacytoma involving the penis is extremely rare. Here, we describe a case of primary extramedullary plasmacytoma of the penis in a 64-year-old man who presented with a palpable penile mass. Nuclear magnetic resonance imaging revealed the presence of a large, round non-encapsulated mass in the perineum. A contrast-enhanced computed tomography scan of the pelvis showed that the mass was located in the tunica albuginea and corpora cavernosa at the base of the penis. The mass encased the urethra and demonstrated no marked enhancement during the arterial phase. The patient underwent successful surgical resection of the tumor. Histologically, the tumor was composed primarily of neoplastic plasma cells that were positive for CD38, vimentin and Ki 67. Postoperatively, the patient recovered well and exhibited no evidence of development of multiple myeloma, local recurrence or distant metastasis at 2 months post-surgery. To the best of our knowledge, our case represents the first documented case of human primary extramedullary plasmacytoma of the penis.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0368-2811
1465-3621
DOI:10.1093/jjco/hyt112