Sensitivity response to coating material thickness for an optical resonant reflective biosensor based on a guided mode resonance filter

• Published in: Biochip journal Vol. 8; no. 1; pp. 35 - 41
• Main Authors: Kim, Bong Kyu, Kim, Kyung-Hyun, Hong, Jongcheol, Kim, Wan-Joong, Ko, Hyunsung, Huh, Chul, Sung, Gun Yong, Jang, Won Ick, Park, Sun Hee, Park, Soo Jun
• Format: Journal Article
• Language: English
• Published: Heidelberg The Korean BioChip Society (KBCS) 01.03.2014; Springer Nature B.V; 한국바이오칩학회
• Subjects: Biomedical Engineering and Bioengineering; Biosensors; Biotechnology; Chemistry; Chemistry and Materials Science; Coating; Coatings; Original Article; Parameter sensitivity; Refractivity; Resonance; Sensitivity; Thickness; Waveguides; 생물공학; Optical resonance reflection biosensor; Sensitivity; Nanostructure; Guided mode reflection filter; Biosensor
• ISSN: 1976-0280; 2092-7843
• DOI: 10.1007/s13206-014-8106-2

Sensitivity is a very important parameter for biosensor applications. We have numerically and experimentally studied the sensitivity and linewidth responses of optical resonant reflective biosensors to the thickness of high refractive index materials coating the grating layer used to create a guided mode. Zero sensitivity, which may create serious problems in biosensors, is obtained when the coating material has a relatively low refractive index and a thin coating thickness (near the cutoff condition in which a high index layer is no longer capable of acting as a waveguide). The sensitivity and linewidth are greatly influenced by the thickness of the coating material. The thickness also has an optimal state, which is a very important factor for designing highly sensitive optical resonant reflective biosensors using a guided mode resonance filter.