Gut microbiota and female health
The gut microbiota is recognized as an endocrine organ with the capacity to influence distant organs and associated biological pathways. Recent advancements underscore the critical role of gut microbial homeostasis in female health; with dysbiosis potentially leading to diseases among women such as...
Saved in:
Published in | World journal of gastroenterology : WJG Vol. 30; no. 12; pp. 1655 - 1662 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
Baishideng Publishing Group Inc
28.03.2024
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The gut microbiota is recognized as an endocrine organ with the capacity to influence distant organs and associated biological pathways. Recent advancements underscore the critical role of gut microbial homeostasis in female health; with dysbiosis potentially leading to diseases among women such as polycystic ovarian syndrome, endometriosis, breast cancer, cervical cancer, and ovarian cancer
Despite this, there has been limited discussion on the underlying mechanisms. This editorial explores the three potential mechanisms through which gut microbiota dysbiosis may impact the development of diseases among women, namely, the immune system, the gut microbiota-estrogen axis, and the metabolite pathway. We focused on approaches for treating diseases in women by addressing gut microbiota imbalances through probiotics, prebiotics supplementation, and fecal microbiota transplantation (FMT). Future studies should focus on determining the molecular mechanisms underlying associations between dysbiosis of gut microbiota and female diseases to realize precision medicine, with FMT emerging as a promising intervention. |
---|---|
Bibliography: | SourceType-Other Sources-1 content type line 63 ObjectType-Editorial-2 ObjectType-Commentary-1 Supported by Science and Technology Plan of Liaoning Province, No. 2022JH2/101500063. Author contributions: Sang LX and Sun SY designed the editorial; Wang MY wrote the draft; Sang LX revised the article for important intellectual content; Sun SY approved the final version, and each author contributed important intellectual content during manuscript drafting and revision. Corresponding author: Si-Yu Sun, MD, PhD, Chief Doctor, Director, Professor, Department of Gastroenterology, Endoscopic Center, Engineering Research Center of Ministry of Education for Minimally Invasive Gastrointestinal Endoscopic Techniques, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Shenyang 110004, Liaoning Province, China. sun-siyu@163.com |
ISSN: | 1007-9327 2219-2840 |
DOI: | 10.3748/wjg.v30.i12.1655 |