Hymenoptera venom allergens

• Published in: Clinical reviews in allergy & immunology Vol. 30; no. 2; pp. 109 - 128
• Main Author: HOFFMAN, Donald R
• Format: Journal Article
• Language: English; German
• Published: Totowa, NJ Humana Press 01.04.2006; Springer Nature B.V
• Subjects: Allergens - chemistry; Allergens - genetics; Allergens - immunology; Amino Acid Sequence; Animals; Ant Venoms - chemistry; Ant Venoms - genetics; Ant Venoms - immunology; Arthropod Venoms - chemistry; Arthropod Venoms - genetics; Arthropod Venoms - immunology; Base Sequence; Bee Venoms - chemistry; Bee Venoms - genetics; Bee Venoms - immunology; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Humans; Hymenoptera - chemistry; Hymenoptera - genetics; Hymenoptera - immunology; Immunopathology; Mass spectrometry; Medical sciences; Molecular Sequence Data; Phylogeny; Terminology as Topic; Venom; Wasp Venoms - chemistry; Wasp Venoms - genetics; Wasp Venoms - immunology; Hyaluronidase; Immunopathology; Allergy; bee; Enzyme; Insecta; ant; antigen 5; Esterases; Antigen; wasp; Phospholipase; Immunology; Arthropoda; Venom; Hydrolases; yellowjacket; hornet; Invertebrata; Hymenoptera; Allergen
• ISSN: 1080-0549; 1559-0267; 1080-0549
• DOI: 10.1385/CRIAI:30:2:109

Hymenoptera venoms each contain a variety of protein allergens. The major components have all been characterized, and most of the amino acid sequences are known. This article concentrates on the use of contemporary techniques including cloning, mass spectrometry and genomics in the characterization of venom allergens, and newer separation techniques for protein isolation. Examples of the use of these techniques with venom proteins are presented.