Synthesis of Phosphorus-Containing Acetamidines Bearing Pharmacophoric Fragments

The reactions of N -adamant-1-ylketeniminophosphonates with heterocyclic amines (pyrrolidine, morpholine, 2,6-dimethylpiperidine, 4-ethylpiperazine, 5-methyl-1,2,4-triazole-3-thione, 2-phenyltetrazole-5-thione) furnished a series of new non-symmetrical C -phosphonylated acetamidines.

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Bibliographic Details
Published inRussian journal of general chemistry Vol. 89; no. 10; pp. 2159 - 2162
Main Authors Alekseeva, K. D., Svintsitskaya, N. I., Dogadina, A. V.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.10.2019
Springer Nature
Springer
Springer Nature B.V
Subjects
Amines
Chemistry
Chemistry and Materials Science
Chemistry, Multidisciplinary
Chemistry/Food Science
Heterocyclic amines
Letters to the Editor
Morpholine
Physical Sciences
Science & Technology
Triazoles
heterocyclic amines
phosphonylated amidines
phosphorus-containing ketenimines
COORDINATION CHEMISTRY
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Summary:The reactions of N -adamant-1-ylketeniminophosphonates with heterocyclic amines (pyrrolidine, morpholine, 2,6-dimethylpiperidine, 4-ethylpiperazine, 5-methyl-1,2,4-triazole-3-thione, 2-phenyltetrazole-5-thione) furnished a series of new non-symmetrical C -phosphonylated acetamidines.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363219100281