Subtypes of transferrin C

Subtypes of transferrin C were studied by means of isoelectric focusing after complete desialylation of transferrin. Family data were consistent with an autosomal co-dominant mode of inheritance. Studies of serum samples from 75 individuals heterozygous for C and another (B or D) variant showed that...

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Bibliographic Details
Published inHuman heredity Vol. 29; no. 5; p. 320
Main Authors Stibler, H, Beckman, G, Silkström, C
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.1979
Subjects
Gene Frequency
Genetic Variation
Heterozygote
Humans
Isoelectric Focusing
Sweden
Transferrin - genetics
Sweden
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Summary:Subtypes of transferrin C were studied by means of isoelectric focusing after complete desialylation of transferrin. Family data were consistent with an autosomal co-dominant mode of inheritance. Studies of serum samples from 75 individuals heterozygous for C and another (B or D) variant showed that the genes (C1 and C2) controlling the C subtypes are allelic to the B and D genes. The C2 gene frequency in Swedes and Swedish Lapps was similar to that found previously in Danes and Germans.
ISSN:0001-5652
DOI:10.1159/000153065