Association between polymorphisms of the APOBEC3G gene and chronic hepatitis B viral infection and hepatitis B virus-related hepatocellular carcinoma

• Published in: World journal of gastroenterology : WJG Vol. 23; no. 2; pp. 232 - 241
• Main Authors: He, Xiu-Ting, Xu, Hong-Qin, Wang, Xiao-Mei, He, Xiu-Shu, Niu, Jun-Qi, Gao, Pu-Jun
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 14.01.2017
• Subjects: Adult; APOBEC-3G Deaminase - genetics; Asian Continental Ancestry Group - genetics; Basic Study; Carcinoma, Hepatocellular - epidemiology; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - virology; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Haplotypes; Hepatitis B virus - isolation & purification; Hepatitis B, Chronic - complications; Hepatitis B, Chronic - epidemiology; Hepatitis B, Chronic - genetics; Hepatitis B, Chronic - virology; Humans; Incidence; Liver Neoplasms - epidemiology; Liver Neoplasms - genetics; Liver Neoplasms - virology; Male; Mass Spectrometry; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; APOBEC3s; Progression; Hepatocellular carcinoma; Hepatitis B viral; Polymorphism

To determine the relationship between five gene single nucleotide polymorphisms and the incidence of hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC). This association study was designed as a retrospective study, including 657 patients with chronic HBV infection (CHB) and 299 hea...