In vitro motility of cells from human epidermoid carcinomas. A study by phase-contrast and reflection-contrast cinematography

The motile behavior of six cell lines derived from human squamous carcinomas (two from the larynx, four from the tongue) was studied by cinematography under phase- and reflection-contrast illumination. The recorded cell activities consist in spreading, stationary and translocation motility, and aggr...

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Bibliographic Details
Published inInternational journal of cancer Vol. 27; no. 5; p. 603
Main Authors Haemmerli, G, Sträuli, P
Format Journal Article
LanguageEnglish
Published United States 15.05.1981
Subjects
Carcinoma, Squamous Cell - pathology
Cell Line
Cell Movement
Humans
Laryngeal Neoplasms - pathology
Microfilming - methods
Microscopy, Phase-Contrast
Neoplasm Invasiveness
Photography - methods
Tongue Neoplasms - pathology
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Summary:The motile behavior of six cell lines derived from human squamous carcinomas (two from the larynx, four from the tongue) was studied by cinematography under phase- and reflection-contrast illumination. The recorded cell activities consist in spreading, stationary and translocation motility, and aggregate formation. Within this common pattern, quantitative modifications ("sub-pattern") are stable properties of the individual cells lines. Such modifications are particularly evident with regard to the dynamic texture of the aggregates which ranges from loose, netlike structures to compact islands with smooth borders. Accordingly, the intensity of cell traffic within and around the aggregates varies considerably. It is discussed to what extent the in vitro motility of the carcinoma cell populations reflects their behavior in the organism and thus the significance of cell movements for invasion.
ISSN:0020-7136
DOI:10.1002/ijc.2910270506