One‐Pot Access to Boron‐Doped Fused Heterocycles via Domino Cyclization of Bis‐Diazidoboranes with Isonitrile

• Published in: Chemistry : a European journal Vol. 29; no. 65; pp. e202302683 - n/a
• Main Authors: Liu, Tong‐Tong, Cui, Yun‐Shu
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 21.11.2023; Wiley Subscription Services, Inc
• Subjects: bis-diazidoborane; Boron; boron-doped fused heterocycles; Chemistry; Chemistry, Multidisciplinary; Cycloaddition; domino reaction; Functional materials; Heterocyclic compounds; one-pot construction; Physical Sciences; Science & Technology; System effectiveness; CYCLOADDITION REACTIONS; cycloaddition; UNIT; boron-doped fused heterocycles; CLICK CHEMISTRY; bis-diazidoborane; one-pot construction; AZIDE; domino reaction; ACCEPTOR
• ISSN: 0947-6539; 1521-3765
• DOI: 10.1002/chem.202302683

Boron‐doped fused heterocycles have shown great potential in the field of functional materials. This study reports on the synthesis of a new class of bis‐diazidoboranes and the discovery of their cycloaddition reaction with isonitriles. Triply fused boron‐doped heterocyclic compounds were constructed in a one‐pot process through a domino cycloaddition, providing an effective route for constructing complex boron‐doped heterocyclic systems. The room temperature domino cyclization reaction of bis‐diazidoboranes with isonitriles was reported for the first time. This one‐step reaction leads to complex boron‐doped fused heterocycles and provides a new strategy for the construction of boron‐doped heterocyclic systems.