CuO/Cu composite nanospheres on a TiO2 nanotube array for amperometric sensing of glucose

• Published in: Mikrochimica acta (1966) Vol. 187; no. 2; p. 123
• Main Authors: Zhou, Zhiru, Zhu, Zanzan, Cui, Feiyun, Shao, Jiahui, Zhou, Hong Susan
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.02.2020; Springer Nature B.V
• Subjects: Analytical Chemistry; Ascorbic acid; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Coated electrodes; Copper; Copper oxides; Dopamine; Electrical measurement; Electrodes; Glucose; Lactose; Microengineering; Nanochemistry; Nanospheres; Nanotechnology; Nanotubes; Original Paper; Sensor arrays; Silver chloride; Sucrose; Titanium dioxide; Uric acid; Wide analytical range; Enzymeless sensing; Glucose sensor; Amperometric sensing; nanotube arrays; CuO-Cu nanospheres; TiO
• ISSN: 0026-3672; 1436-5073; 1436-5073
• DOI: 10.1007/s00604-019-4099-9

A non-enzymatic glucose sensor based on the use of CuO-Cu nanospheres placed on a TiO2 nanotube (TNT) array with excellent performance is described. The electrode was fabricated by coating the CuO-Cu nanospheres onto the TNT array through electrochemical deposition. The CuO-Cu nanospheres with a diameter of ~200 nm are well dispersed on the TNT surface, which warrants smooth interaction and a 3D nanostructure with high uniformity. The modified electrode was then used for amperometric determination of glucose in 0.1 M NaOH solution. Figures of merit include (a) a typical working voltage of 0.65 V (vs. Ag/AgCl). (b) a linear range as wide as from 0.2–90 mM, (c) good sensitivity (234 μA mM −1  cm −2 ), and a 19 nM lower detection limit. The sensor is selective over ascorbic acid (AA), dopamine (DA), uric acid (UA), lactose, sucrose, and fructose. Graphical abstract