Observational cohort studies: lessons learnt from the University of Toronto Psoriatic Arthritis Program

Observational cohorts have emerged as important resources to study course and prognosis of chronic disease, and also facilitate phenotype definition for genetic studies. We describe the development and accomplishments of the PsA cohort at the University of Toronto as an example of an observational c...

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Bibliographic Details
Published inRheumatology (Oxford, England) Vol. 50; no. 1; pp. 25 - 31
Main Authors Gladman, Dafna D, Chandran, Vinod
Format Journal Article
LanguageEnglish
Published England 01.01.2011
Subjects
Adult
Arthritis, Psoriatic - epidemiology
Arthritis, Psoriatic - genetics
Arthritis, Psoriatic - physiopathology
Canada - epidemiology
Cohort Studies
Female
Genetic Predisposition to Disease
Humans
Incidence
Male
Middle Aged
Phenotype
Prevalence
Psoriasis - epidemiology
Psoriasis - genetics
Psoriasis - physiopathology
Severity of Illness Index
Spondylitis, Ankylosing - epidemiology
Spondylitis, Ankylosing - genetics
Spondylitis, Ankylosing - physiopathology
Canada
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Summary:Observational cohorts have emerged as important resources to study course and prognosis of chronic disease, and also facilitate phenotype definition for genetic studies. We describe the development and accomplishments of the PsA cohort at the University of Toronto as an example of an observational cohort that has allowed the description of disease manifestations, course and prognosis of PsA. We also describe the development of an international collaboration based on this cohort, which will further be used to study the incidence, prevalence and predictive factors for the development of PsA among patients with psoriasis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/keq262