Gamma Co-60 ray irradiation synthesis of dextran stabilized selenium nanoparticles and their antioxidant activity

• Published in: Materials chemistry and physics Vol. 205; pp. 29 - 34
• Main Authors: Hien, Nguyen Quoc, Tuan, Phan Dinh, Phu, Dang Van, Quoc, Le Anh, Lan, Nguyen Thi Kim, Duy, Nguyen Ngoc, Hoa, Tran Thai
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.02.2018; Elsevier BV
• Subjects: Antioxidant; Antioxidants; Chemical synthesis; Dextran; Gamma irradiation; Gamma ray; Gamma rays; Image transmission; Nanoparticles; Powder; Purity; Selenium; Selenium nanoparticles; Spray drying; Sterilization; Dextran; Gamma ray; Antioxidant; Selenium nanoparticles; Powder
• ISSN: 0254-0584; 1879-3312
• DOI: 10.1016/j.matchemphys.2017.11.003

Selenium nanoparticles (SeNPs) with diameter of ∼74 nm were synthesized by gamma Co-60 ray irradiation of H2SeO3/dextran solution. The SeNPs were characterized by UV–Vis spectroscopy spectrum and transmission electron microscope (TEM) images. The effect of pH of H2SeO3/dextran solutions before gamma irradiation on the size of SeNPs was investigated. The SeNPs/dextran powder was also prepared by spray drying technique and the purity was verified by energy dispersive X-ray (EDX) analysis. The ATBS•+ radical scavenging ability and reducing power of SeNPs were assessed. Results showed that SeNPs/dextran with concentration of 25–100 ppm exhibited high antioxidant activity. The as-prepared SeNPs/dextran powder with selenium content of ∼2.51% (wt%) was of high purity. The influence of gamma Co-60 ray sterilization at dose of 25 kGy on the characteristics of SeNPs/dextran powder was also examined. [Display omitted] •SeNPs were synthesized by γ-irradiation of 2.5 mM H2SeO3/1% dextran solution.•pH 6 favored to obtain SeNPs ∼74 nm with the narrow size distribution.•SeNPs/dextran powder prepared by spray drying technique was high purity.•SeNPs exhibited highly antioxidant activity.•Radiation sterilization of SeNPs/dextran powder did not noticeable change in size.