Primary adenosquamous cell carcinoma of the pancreas: a case report with a review of the Korean literature

The most common pancreatic cancer is adenocarcinoma. Primary adenosquamous cell carcinoma of the pancreas is very rare and aggressive. A 46-year-old man presented with a 3-month history of dyspepsia and a 7-kg weight loss. The physical examination showed tenderness of the right upper quadrant of the...

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Published inThe Korean journal of internal medicine Vol. 26; no. 3; pp. 348 - 351
Main Authors Na, Youn Ju, Shim, Ki-Nam, Cho, Min Sun, Sung, Sun Hee, Jung, Sung-Ae, Yoo, Kwon, Chung, Kyu Won
Format Journal Article
LanguageEnglish
Published Korea (South) The Korean Association of Internal Medicine 01.09.2011
대한내과학회
Subjects
Amylases - blood
Biopsy, Fine-Needle
CA-19-9 Antigen - blood
Carcinoma, Adenosquamous - blood
Carcinoma, Adenosquamous - complications
Carcinoma, Adenosquamous - diagnosis
Carcinoma, Adenosquamous - pathology
Case Report
Duodenoscopy
Duodenum - pathology
Humans
Intestinal Mucosa - pathology
Lipase - blood
Male
Middle Aged
Neoplasm Invasiveness
Pancreatic Neoplasms - blood
Pancreatic Neoplasms - complications
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - pathology
Tomography, X-Ray Computed
내과학
Carcinoma, Adenosquamous
Pancreas
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Summary:The most common pancreatic cancer is adenocarcinoma. Primary adenosquamous cell carcinoma of the pancreas is very rare and aggressive. A 46-year-old man presented with a 3-month history of dyspepsia and a 7-kg weight loss. The physical examination showed tenderness of the right upper quadrant of the abdomen. There was no jaundice. Amylase and lipase were elevated. CA 19-9 was elevated to 566.7 U/mL. Gastroduodenoscopy showed a hard ulceroinfiltrative mass with a yellowish exudate that bled readily on touch in the second portion of the duodenum. Abdominal computed tomography showed a 7.1 × 6.3-cm heterogeneously enhancing mass in the pancreatic head. The pancreatic mass had invaded the duodenum wall, gastric antrum, and gastroduodenal artery sheath. Fine-needle aspiration biopsy of the pancreatic mass revealed adenosquamous cell carcinoma, anaplastic type. We concluded that an adenosquamous cell carcinoma of pancreas had invaded the duodenal mucosa causing ulceration.
Bibliography:ObjectType-Case Study-3
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ObjectType-Feature-5
ObjectType-Report-2
ObjectType-Article-4
G704-001640.2011.26.3.001
ISSN:1226-3303
2005-6648
DOI:10.3904/kjim.2011.26.3.348