In vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity of Murraya koenigii leaf extract intercedes ZnO nanoparticles

Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant,...

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Published inLuminescence (Chichester, England) Vol. 38; no. 7; pp. 1139 - 1148
Main Authors Sharma, Avinash, Nagraik, Rupak, Venkidasamy, Baskar, Khan, Azhar, Dulta, Kanika, Kumar Chauhan, Pankaj, Kumar, Deepak, Shin, Dong‐Soo
Format Journal Article
LanguageEnglish
Published England Wiley Subscription Services, Inc 01.07.2023
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Summary:Nanotechnology is an emerging field with tremendous potential and usage of medicinal plants and green preparation of nanoparticles (NPs) is one of the widely explored areas. These have been shown to be effective against different biological activities such as diabetes mellitus, cancer, antioxidant, antimicrobial, etc. The current studies focus on the green synthesis of zinc NPs (ZnO NPs) from aqueous leaf extract of Murraya koenigii (MK). The synthesized Murraya koeingii zinc oxide NPs (MK ZnO NPs) were characterized using UV–visible spectroscopy, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy‐dispersive spectrum (EDS) and cyclic voltammetry (CV). The synthesized MK ZnO NPs were evaluated for their in vitro antidiabetic, antioxidant, antimicrobial, and cytotoxic activity. They demonstrated significant antidiabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity. Murraya koeingii zinc oxide nanoparticles (MK ZnONPs) prepared via green synthesis, characterized and evaluated for their biological activities. The particle showed significant anti‐diabetic and cytotoxic activity, as well as moderate free‐radical scavenging and antibacterial activity.
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ISSN:1522-7235
1522-7243
DOI:10.1002/bio.4244