Aqueous Extracts of Wild Mushrooms Show Antimicrobial and Antiadhesion Activities against Bacteria and Fungi

• Published in: Phytotherapy research Vol. 31; no. 12; pp. 1971 - 1976
• Main Authors: Klančnik, Anja, Megušar, Polona, Sterniša, Meta, Jeršek, Barbara, Bucar, Franz, Smole Možina, Sonja, Kos, Janko, Sabotič, Jerica
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.12.2017
• Subjects: adhesion; Adhesion tests; Agaricales - chemistry; Anti-Bacterial Agents - therapeutic use; Anti-Infective Agents - therapeutic use; antiadhesion activity; Antiinfectives and antibacterials; antimicrobial activity; Antimicrobial agents; Bacteria; Basidiocarps; basidiomycete; Bioactive compounds; Food chains; Food contamination; Fungi; Gram-negative bacteria; Microbial contamination; Microorganisms; Mushrooms; Pleurotus ostreatus; Pollution control; Polystyrene; Polystyrene resins; basidiomycete; adhesion; antimicrobial activity; antiadhesion activity
• ISSN: 0951-418X; 1099-1573
• DOI: 10.1002/ptr.5934

Mushrooms represent promising sources of novel bioactive compounds and can be applied as innovative strategies to control microbial contamination and infection via the food chain. We characterized aqueous extracts from 21 wild basidiomycete mushrooms and the cultivated oyster mushroom, Pleurotus ostreatus, as putative sources of antimicrobial and antiadhesive compounds. Broth microdilutions and adhesion to a polystyrene surface were evaluated on Gram‐positive and Gram‐negative bacteria and on fungi. The aqueous extracts tested showed antimicrobial and antiadhesive activities against these microorganisms. Biochemical analyses of the P. ostreatus extract indicated the involvement of several compounds with different molecular masses. Copyright © 2017 John Wiley & Sons, Ltd.