Ossifying fibromyxoid tumor: Fine‐needle aspiration cytology findings of a rare soft tissue neoplasm

• Published in: Diagnostic cytopathology Vol. 48; no. 4; pp. 396 - 400
• Main Authors: Kumari, Neha, Anthony, Michael L., Durgapal, Prashant, Joshi, Prashant P., Rajput, Deepak, Singh, Ashok
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.04.2020; Wiley Subscription Services, Inc
• Subjects: Cellular biology; cytology; fibrous; lamellar bone; myxoid; osseous; peripheral calcification; Sarcoma; Tumors; fibrous; cytology; osseous; lamellar bone; peripheral calcification; myxoid
• ISSN: 8755-1039; 1097-0339
• DOI: 10.1002/dc.24382

Ossifying fibromyxoid tumors (OFMTs) are rare tumors of uncertain origin and intermediate (rarely metastasizing) biologic potential, with characteristic morphology of an encapsulated tumor containing polygonal cells in an abundant fibromyxoid matrix surrounded by a peripheral layer of metaplastic lamellar bone. FNA cytology of OFMT has not been sufficiently reported and till date cytological features of only seven cases have been reported so far. We report another case of OFMT in a 55‐year‐old female presenting with longstanding swelling in thigh. On fine‐needle aspiration, a tumor with moderate cellularity and myxoid areas was seen; coupled with compatible radiological findings, a diagnosis of OFMT was suggested. Establishing a correct diagnosis is important as although OFMT is benign in nature, local recurrences or rarely distant metastasis have been seen of this tumor. Hence, a high degree of suspicion with radiological correlation is of utmost importance for identification of this entity.